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Granzyme B Is an Essential Mediator in CD8(+) T Cell Killing of Theileria parva-Infected Cells

There is established evidence that cytotoxic CD8(+) T cells are important mediators of immunity against the bovine intracellular protozoan parasite Theileria parva. However, the mechanism by which the specific CD8(+) T cells kill parasitized cells is not understood. Although the predominant pathway...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Yang, Jie, Pemberton, Alan, Morrison, W. Ivan, Connelley, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300629/
https://ncbi.nlm.nih.gov/pubmed/30323022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00386-18
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