Extensive Polymorphism and Evidence of Immune Selection in a Highly Dominant Antigen Recognized by Bovine CD8 T Cells Specific for Theileria annulata

Although parasite strain-restricted CD8 T cell responses have been described for several protozoa, the precise role of antigenic variability in immunity is poorly understood. The tick-borne protozoan parasite Theileria annulata infects leukocytes and causes an acute, often fatal lymphoproliferative...

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Bibliografiska uppgifter
Huvudupphovsmän: MacHugh, Niall D., Weir, William, Burrells, Alison, Lizundia, Regina, Graham, Simon P., Taracha, Evans L., Shiels, Brian R., Langsley, Gordon, Morrison, W. Ivan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2011
Ämnen:
Microbial Immunity and Vaccines
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088144/
https://ncbi.nlm.nih.gov/pubmed/21300773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01285-10
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