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Intrinsic Defects in CD8 T Cells with Aging Contribute to Impaired Primary Antiviral Responses
Aging is associated with altered immune responses, particularly with a diminished CD8 T cell response. Although both intrinsic and extrinsic factors are hypothesized to impact this decreased T cell response, the direct evidence of an intrinsic deficiency in virus-specific CD8 T cells is limited. In...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3677037/ https://ncbi.nlm.nih.gov/pubmed/23473930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2013.02.027 |
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