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Gram-Scale Synthesis of the A’B’-Subunit of Angelmicin B

[Image: see text] A gram-scale enantiospecific synthesis of the A’B’-subunit of angelmicin B is reported. The synthesis involves a Lewis acid-catalyzed contrasteric Diels–Alder reaction and a tandem silyl zincate 1,6-addition/enolate oxidation sequence.

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Autors principals: Milgram, Benjamin C., Liau, Brian B., Shair, Matthew D.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237735/
https://ncbi.nlm.nih.gov/pubmed/22084899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol202728v
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