Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells

Cytotoxic T lymphocytes (CTLs) modified with chimeric antigen receptors (CARs) for adoptive immunotherapy of hematologic malignancies are effective in preclinical models and are being tested in several clinical trials. Although CTLs bearing stably expressed CARs generated by integrating viral vector...

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Detalhes bibliográficos
Main Authors: Barrett, David M., Zhao, Yangbing, Liu, Xiaojun, Jiang, Shuguang, Carpenito, Carmine, Kalos, Michael, Carroll, Richard G., June, Carl H., Grupp, Stephan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237694/
https://ncbi.nlm.nih.gov/pubmed/21838572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.070
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