Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells

Cytotoxic T lymphocytes (CTLs) modified with chimeric antigen receptors (CARs) for adoptive immunotherapy of hematologic malignancies are effective in preclinical models and are being tested in several clinical trials. Although CTLs bearing stably expressed CARs generated by integrating viral vector...

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Autors principals: Barrett, David M., Zhao, Yangbing, Liu, Xiaojun, Jiang, Shuguang, Carpenito, Carmine, Kalos, Michael, Carroll, Richard G., June, Carl H., Grupp, Stephan A.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237694/
https://ncbi.nlm.nih.gov/pubmed/21838572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.070
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