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Constitutive Expression of Short Hairpin RNA in Vivo Triggers Buildup of Mature Hairpin Molecules

RNA interference (RNAi) has become the cornerstone technology for studying gene function in mammalian cells. In addition, it is a promising therapeutic treatment for multiple human diseases. Virus-mediated constitutive expression of short hairpin RNA (shRNA) has the potential to provide a permanent...

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Détails bibliographiques
Auteurs principaux: Ahn, M., Witting, S.R., Ruiz, R., Saxena, R., Morral, N.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237692/
https://ncbi.nlm.nih.gov/pubmed/21780944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.234
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