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Constitutive Expression of Short Hairpin RNA in Vivo Triggers Buildup of Mature Hairpin Molecules

RNA interference (RNAi) has become the cornerstone technology for studying gene function in mammalian cells. In addition, it is a promising therapeutic treatment for multiple human diseases. Virus-mediated constitutive expression of short hairpin RNA (shRNA) has the potential to provide a permanent...

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Detalhes bibliográficos
Main Authors: Ahn, M., Witting, S.R., Ruiz, R., Saxena, R., Morral, N.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237692/
https://ncbi.nlm.nih.gov/pubmed/21780944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.234
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