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Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells.
The ability of tumor cells to develop simultaneous resistance to structurally different cytotoxic drugs constitutes a major problem in cancer chemotherapy. It was previously demonstrated that multidrug-resistant Chinese hamster cell lines contain an amplified, transcriptionally active DNA sequence d...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1986
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3459187/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.12.4538 |
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