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Cellular Mechanisms of Restored β-Cell Tolerance Mediated by Protective Alleles of Idd3 and Idd5

Type 1 diabetes genes within the interleukin (IL)-2, cytotoxic T-lymphocyte--associated protein 4 (CTLA-4), and natural resistance-associated macrophage protein (NRAMP1) pathways influence development of autoimmune diabetes in humans and NOD mice. In NOD mice, when present together, protective allel...

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Autors principals: Hamilton-Williams, Emma E., Cheung, Jocelyn, Rainbow, Daniel B., Hunter, Kara M., Wicker, Linda S., Sherman, Linda A.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237671/
https://ncbi.nlm.nih.gov/pubmed/22106155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0790
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