Targeted Loss of GHR Signaling in Mouse Skeletal Muscle Protects Against High-Fat Diet–Induced Metabolic Deterioration

Growth hormone (GH) exerts diverse tissue-specific metabolic effects that are not revealed by global alteration of GH action. To study the direct metabolic effects of GH in the muscle, we specifically inactivated the growth hormone receptor (ghr) gene in postnatal mouse skeletal muscle using the Cre...

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Detaylı Bibliyografya
Asıl Yazarlar: Vijayakumar, Archana, Wu, YingJie, Sun, Hui, Li, Xiaosong, Jeddy, Zuha, Liu, Chengyu, Schwartz, Gary J., Yakar, Shoshana, LeRoith, Derek
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2012
Konular:
Metabolism
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237669/
https://ncbi.nlm.nih.gov/pubmed/22187377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0814
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