Deletion of Growth Hormone Receptors in Postnatal Skeletal Muscle of Male Mice Does Not Alter Muscle Mass and Response to Pathological Injury

In this study, we investigated whether loss of GH receptor (GHR) signaling in postnatal skeletal muscle alters muscle mass and regenerative ability in adult mice and whether this was dependent on IGF-1 receptor (IGF-1R) signaling. To do so, we used mouse models with skeletal muscle-specific loss of...

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Vydáno v:Endocrinology
Hlavní autoři: Vijayakumar, Archana, Buffin, Nicholas J., Gallagher, Emily J., Blank, Jeffrey, Wu, Yingjie, Yakar, Shoshana, LeRoith, Derek
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2013
Témata:
Growth Hormone-Somatostatin-GRH
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398538/
https://ncbi.nlm.nih.gov/pubmed/23861377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1209
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