Curative Effect of 18β-Glycyrrhetinic Acid in Experimental Visceral Leishmaniasis Depends on Phosphatase-Dependent Modulation of Cellular MAP Kinases

We earlier showed that 18β-glycyrrhetinic acid (GRA), a pentacyclic triterpenoid from licorice root, could completely cure visceral leishmaniasis in BALB/c mouse model. This was associated with induction of nitric oxide and proinflammatory cytokine production through the up regulation of NF-κB. In t...

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Hlavní autoři: Ukil, Anindita, Kar, Susanta, Srivastav, Supriya, Ghosh, Kuntal, Das, Pijush K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237588/
https://ncbi.nlm.nih.gov/pubmed/22194991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029062
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