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Complement C3 Deficiency Attenuates Chronic Hypoxia-Induced Pulmonary Hypertension in Mice

BACKGROUND: Evidence suggests a role of both innate and adaptive immunity in the development of pulmonary arterial hypertension. The complement system is a key sentry of the innate immune system and bridges innate and adaptive immunity. To date there are no studies addressing a role for the compleme...

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Hlavní autoři: Bauer, Eileen M., Zheng, Han, Comhair, Suzy, Erzurum, Serpil, Billiar, Timothy R., Bauer, Philip M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237464/
https://ncbi.nlm.nih.gov/pubmed/22194859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028578
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