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The role of SIRT1 in tumorigenesis

NAD-dependent Class III histone deacetylase SIRT1 is a multiple functional protein and has been demonstrated critically involved in stress response, cellular metabolism and aging through deacetylating variety of substrates including p53, forkhead transcription factors, PGC-1α, NF-κB, Ku70 and histon...

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Bibliografske podrobnosti
Main Authors: Li, Kai, Luo, Jianyuan
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237400/
https://ncbi.nlm.nih.gov/pubmed/22180829
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