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Janus-faced role of SIRT1 in tumorigenesis

Silent mating type information regulation 1 (Sirtuin 1; SIRT1) has been reported to regulate various physiological events, such as aging and metabolism, via deacetylation of histone and nonhistone proteins. Notably, cumulative evidence supports the notion that SIRT1 has a Janus-faced role in tumorig...

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Autori principali: Song, Na-Young, Surh, Young-Joon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Inc 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499659/
https://ncbi.nlm.nih.gov/pubmed/23050959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06762.x
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