Selective regulation of trypsin gene expression by calcium and by glucose starvation in a rat exocrine pancreas cell line.
Treatment of the rat pancreatic acinar cell line AR4-2J with the calcium ionophore A23187 selectively increases, within a few hours, the steady-state level of trypsin mRNA. Addition of the tumor-promoting phorbol ester phorbol 12-myristate 13-acetate potentiates the calcium-induced increase. The mRN...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1986
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3086879/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.12.4292 |
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