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Selective regulation of trypsin gene expression by calcium and by glucose starvation in a rat exocrine pancreas cell line.

Treatment of the rat pancreatic acinar cell line AR4-2J with the calcium ionophore A23187 selectively increases, within a few hours, the steady-state level of trypsin mRNA. Addition of the tumor-promoting phorbol ester phorbol 12-myristate 13-acetate potentiates the calcium-induced increase. The mRN...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Stratowa, C, Rutter, W J
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1986
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323718/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3086879/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.12.4292
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