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Selective regulation of trypsin gene expression by calcium and by glucose starvation in a rat exocrine pancreas cell line.

Treatment of the rat pancreatic acinar cell line AR4-2J with the calcium ionophore A23187 selectively increases, within a few hours, the steady-state level of trypsin mRNA. Addition of the tumor-promoting phorbol ester phorbol 12-myristate 13-acetate potentiates the calcium-induced increase. The mRN...

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Autors principals: Stratowa, C, Rutter, W J
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC323718/
https://ncbi.nlm.nih.gov/pubmed/3086879
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