Vaccination with M2e-Based Multiple Antigenic Peptides: Characterization of the B Cell Response and Protection Efficacy in Inbred and Outbred Mice

BACKGROUND: The extracellular domain of the influenza A virus protein matrix protein 2 (M2e) is remarkably conserved between various human isolates and thus is a viable target antigen for a universal influenza vaccine. With the goal of inducing protection in multiple mouse haplotypes, M2e-based mult...

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Bibliografiske detaljer
Main Authors: Wolf, Amaya I., Mozdzanowska, Krystyna, Williams, Katie L., Singer, David, Richter, Monique, Hoffmann, Ralf, Caton, Andrew J., Otvos, Laszlo, Erikson, Jan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236751/
https://ncbi.nlm.nih.gov/pubmed/22180783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028445
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