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Effects of multiple doses of cyclophosphamide on mouse testes: Accessing the germ cells lost, and the functional damage of stem cells

Spermatogenesis is sensitive to the chemotherapeutic drug cyclophosphamide, which decreases the patients’ sperm count. Since the recovery of fertility is dependent on regeneration from stem cells, in the present study we evaluated the ability of cyclophosphamide-exposed stem spermatogonia from mice...

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Detalhes bibliográficos
Main Authors: Drumond, Ana Luiza, Weng, Connie C., Wang, Gensheng, Chiarini-Garcia, Helio, Eras-Garcia, Leticia, Meistrich, Marvin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236636/
https://ncbi.nlm.nih.gov/pubmed/22001253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2011.09.010
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