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Hormonal Suppression Restores Fertility in Irradiated Mice from both Endogenous and Donor-Derived Stem Spermatogonia

Irradiation interrupts spermatogenesis and causes prolonged sterility in male mammals. Hormonal suppression treatment with gonadotropin-releasing hormone (GnRH) analogues has restored spermatogenesis in irradiated rats, but similar attempts were unsuccessful in irradiated mice, monkeys, and humans....

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Detalhes bibliográficos
Main Authors: Wang, Gensheng, Shao, Shan H., Weng, Connie C. Y., Wei, Caimiao, Meistrich, Marvin L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923290/
https://ncbi.nlm.nih.gov/pubmed/20584762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq191
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