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The hydrazide/hydrazone click reaction as a biomolecule labeling strategy for M(CO)(3) (M = Re, (99m)Tc) radiopharmaceuticals()
Facile reactivity of hydrazides and aldehydes was explored as potential coupling partners for incorporation into M(CO)(3) (M = Re, (99m)Tc) based radiopharmaceuticals. Both ‘click, then chelate’ and ‘prelabel, then click’ synthetic routes produced identical products in high yields and lacked metal-h...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3236597/ https://ncbi.nlm.nih.gov/pubmed/22044929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc15451f |
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