The hydrazide/hydrazone click reaction as a biomolecule labeling strategy for M(CO)(3) (M = Re, (99m)Tc) radiopharmaceuticals()

Facile reactivity of hydrazides and aldehydes was explored as potential coupling partners for incorporation into M(CO)(3) (M = Re, (99m)Tc) based radiopharmaceuticals. Both ‘click, then chelate’ and ‘prelabel, then click’ synthetic routes produced identical products in high yields and lacked metal-h...

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Bibliographic Details
Main Authors:	Ganguly, Tanushree, Kasten, Benjamin B., Bučar, Dejan-Krešimir, MacGillivray, Leonard R., Berkman, Clifford E., Benny, Paul D.
Format:	Artigo
Language:	Inglês
Published:	2011
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3236597/ https://ncbi.nlm.nih.gov/pubmed/22044929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc15451f
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The hydrazide/hydrazone click reaction as a biomolecule labeling strategy for M(CO)(3) (M = Re, (99m)Tc) radiopharmaceuticals()

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