Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts.

Mouse B lymphocytes can be activated polyclonally by bacterial lipopolysaccharide (LPS) to secrete Ig and perform Ig class switch. In the presence of the T-cell lymphokine B-cell differentiation factor, the frequency of IgG1-secreting cells is drastically enhanced. We show here that IgG1-secreting B...

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Bibliographic Details
Main Authors: Radbruch, A, Müller, W, Rajewsky, K
Format: Artigo
Language:Inglês
Published: 1986
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC323643/
https://ncbi.nlm.nih.gov/pubmed/3086872
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