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Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts.

Mouse B lymphocytes can be activated polyclonally by bacterial lipopolysaccharide (LPS) to secrete Ig and perform Ig class switch. In the presence of the T-cell lymphokine B-cell differentiation factor, the frequency of IgG1-secreting cells is drastically enhanced. We show here that IgG1-secreting B...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Radbruch, A, Müller, W, Rajewsky, K
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323643/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3086872/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.3954
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