Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts.
Mouse B lymphocytes can be activated polyclonally by bacterial lipopolysaccharide (LPS) to secrete Ig and perform Ig class switch. In the presence of the T-cell lymphokine B-cell differentiation factor, the frequency of IgG1-secreting cells is drastically enhanced. We show here that IgG1-secreting B...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1986
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3086872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.3954 |
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