The Importance of Being Profiled: Improving Drug Candidate Safety and Efficacy Using Ion Channel Profiling

Profiling of putative lead compounds against a representative panel of relevant enzymes, receptors, ion channels, and transporters is a pragmatic approach to establish a preliminary view of potential issues that might later hamper development. An early idea of which off-target activities must be min...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kaczorowski, Gregory J., Garcia, Maria L., Bode, Jacob, Hess, Stephen D., Patel, Umesh A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Research Foundation 2011
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236397/
https://ncbi.nlm.nih.gov/pubmed/22171219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2011.00078
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge