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Automated Electrophysiology Makes the Pace for Cardiac Ion Channel Safety Screening

The field of automated patch-clamp electrophysiology has emerged from the tension between the pharmaceutical industry’s need for high-throughput compound screening versus its need to be conservative due to regulatory requirements. On the one hand, hERG channel screening was increasingly requested fo...

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Detalhes bibliográficos
Main Authors: Möller, Clemens, Witchel, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222877/
https://ncbi.nlm.nih.gov/pubmed/22131974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2011.00073
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