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NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights

Structural chromosomal rearrangements of the Nucleoporin 98 gene (NUP98), primarily balanced translocations and inversions, are associated with a wide array of hematopoietic malignancies. NUP98 is known to be fused to at least 28 different partner genes in patients with hematopoietic malignancies, i...

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Autors principals: Gough, Sheryl M., Slape, Christopher I., Aplan, Peter D.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236115/
https://ncbi.nlm.nih.gov/pubmed/21948299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-328880
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