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The fusion partner specifies the oncogenic potential of NUP98 fusion proteins

NUP98 is among the most promiscuously translocated genes in hematological diseases. Among the 28 known fusion partners, there are two categories: homeobox genes and non-homeobox genes. The homeobox fusion partners are well-studied in animal models, resulting in HoxA cluster overexpression and hemato...

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Detalhes bibliográficos
Main Authors: Saw, Jesslyn, Curtis, David J., Hussey, Damian J., Dobrovic, Alexander, Aplan, Peter D., Slape, Christopher I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883578/
https://ncbi.nlm.nih.gov/pubmed/24090997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.09.013
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