Rapid, non-invasive imaging of alphaviral brain infection: Reducing animal numbers and morbidity to identify efficacy of potential vaccines and antivirals

Rapid and accurate identification of disease progression are key factors in testing novel vaccines and antivirals against encephalitic alphaviruses. Typical efficacy studies utilize a large number of animals and severe morbidity or mortality as an endpoint. New technologies provide a means to reduce...

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Detalhes bibliográficos
Main Authors: Patterson, Michael, Poussard, Allison, Taylor, Katherine, Seregin, Alexey, Smith, Jeanon, Peng, Bi-Hung, Walker, Aida, Linde, Jenna, Smith, Jennifer, Salazar, Milagros, Paessler, Slobodan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236093/
https://ncbi.nlm.nih.gov/pubmed/22001884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.09.130
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