Oral ezatiostat HCl (Telintra(®), TLK199) and Idiopathic Chronic Neutropenia (ICN): a case report of complete response of a patient with G-CSF resistant ICN following treatment with ezatiostat, a glutathione S-transferase P1-1 (GSTP1-1) inhibitor

Idiopathic chronic neutropenia (ICN) describes a heterogeneous group of hematologic diseases characterized by low circulating neutrophil levels often associated with recurrent fevers, chronic mucosal inflammation, and severe systemic infections. The severity and risk of complications, including seri...

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Bibliographic Details
Main Authors: Lyons, Roger M, Wilks, Sharon T, Young, Shelby, Brown, Gail L
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235963/
https://ncbi.nlm.nih.gov/pubmed/22047626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-4-43
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