Membrane Changes Associated with Platelet Activation: EXPOSURE OF ACTIN ON THE PLATELET SURFACE AFTER THROMBIN-INDUCED SECRETION

Por George, James N., Lyons, Roger M., Morgan, Rebecca K.
Publicado em 1980

Oral ezatiostat HCl (Telintra(®), TLK199) and Idiopathic Chronic Neutropenia (ICN): a case report of complete response of a patient with G-CSF resistant ICN following treatment wit...

Por Lyons, Roger M, Wilks, Sharon T, Young, Shelby, Brown, Gail L
Publicado em 2011

Treatment of Acquired von Willebrand Syndrome and Prevention of Bleeding Postautologous Stem Cell Transplant during Severe Pancytopenia with IVIG

Por Zoghi, Behyar, Shaughnessy, Paul, Lyons, Roger M., Helmer, Richard, Bachier, Carlos, LeMaistre, C. Frederick
Publicado no Case Rep Hematol (2015)

Phase 2, single-arm trial to evaluate the effectiveness of darbepoetin alfa for correcting anaemia in patients with myelodysplastic syndromes

Por Gabrilove, Janice, Paquette, Ronald, Lyons, Roger M, Mushtaq, Chaudhry, Sekeres, Mikkael A, Tomita, Dianne, Dreiling, Lyndah
Publicado em 2008

A randomized, double-blind, placebo-controlled phase 2 study evaluating the efficacy and safety of romiplostim treatment of patients with low or intermediate-1 risk myelodysplastic...

Por Wang, Eunice S, Lyons, Roger M, Larson, Richard A, Gandhi, Sunil, Liu, Delong, Matei, Carmen, Scott, Bart, Hu, Kuolung, Yang, Allen S
Publicado em 2012

Phase 1 dose-ranging study of ezatiostat hydrochloride in combination with lenalidomide in patients with non-deletion (5q) low to intermediate-1 risk myelodysplastic syndrome (MDS)

Por Raza, Azra, Galili, Naomi, Mulford, Deborah, Smith, Scott E, Brown, Gail L, Steensma, David P, Lyons, Roger M, Boccia, Ralph, Sekeres, Mikkael A, Garcia-Manero, Guillermo, Mesa, Ruben A
Publicado em 2012

CHAMPION-1: a phase 1/2 study of once-weekly carfilzomib and dexamethasone for relapsed or refractory multiple myeloma

Por Berenson, James R., Cartmell, Alan, Bessudo, Alberto, Lyons, Roger M., Harb, Wael, Tzachanis, Dimitrios, Agajanian, Richy, Boccia, Ralph, Coleman, Morton, Moss, Robert A., Rifkin, Robert M., Patel, Priti, Dixon, Sandra, Ou, Ying, Anderl, Janet, Aggarwal, Sanjay, Berdeja, Jesus G.
Publicado no Blood (2016)

Interim analysis of safety and efficacy of ruxolitinib in patients with myelofibrosis and low platelet counts

Por Talpaz, Moshe, Paquette, Ronald, Afrin, Lawrence, Hamburg, Solomon I, Prchal, Josef T, Jamieson, Katarzyna, Terebelo, Howard R, Ortega, Gregory L, Lyons, Roger M, Tiu, Ramon V, Winton, Elliott F, Natrajan, Kavita, Odenike, Olatoyosi, Claxton, David, Peng, Wei, O’Neill, Peter, Erickson-Viitanen, Susan, Leopold, Lance, Sandor, Victor, Levy, Richard S, Kantarjian, Hagop M, Verstovsek, Srdan
Publicado em 2013

Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial

Por Verstovsek, Srdan, Mesa, Ruben A., Gotlib, Jason, Gupta, Vikas, DiPersio, John F., Catalano, John V., Deininger, Michael W. N., Miller, Carole B., Silver, Richard T., Talpaz, Moshe, Winton, Elliott F., Harvey, Jimmie H., Arcasoy, Murat O., Hexner, Elizabeth O., Lyons, Roger M., Paquette, Ronald, Raza, Azra, Jones, Mark, Kornacki, Deanna, Sun, Kang, Kantarjian, Hagop
Publicado no J Hematol Oncol (2017)

The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis

Por Verstovsek, Srdan, Mesa, Ruben A., Gotlib, Jason, Levy, Richard S., Gupta, Vikas, DiPersio, John F., Catalano, John V., Deininger, Michael, Miller, Carole, Silver, Richard T., Talpaz, Moshe, Winton, Elliott F., Harvey, Jimmie H., Arcasoy, Murat O., Hexner, Elizabeth, Lyons, Roger M., Paquette, Ronald, Raza, Azra, Vaddi, Kris, Erickson-Viitanen, Susan, Sun, William, Sandor, Victor, Kantarjian, Hagop M.
Publicado em 2013

Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I

Por Verstovsek, Srdan, Mesa, Ruben A., Gotlib, Jason, Levy, Richard S., Gupta, Vikas, DiPersio, John F., Catalano, John V., Deininger, Michael W.N., Miller, Carole B., Silver, Richard T., Talpaz, Moshe, Winton, Elliott F., Harvey, Jimmie H., Arcasoy, Murat O., Hexner, Elizabeth O., Lyons, Roger M., Raza, Azra, Vaddi, Kris, Sun, William, Peng, Wei, Sandor, Victor, Kantarjian, Hagop
Publicado no Haematologica (2015)

A Double-Blind Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis

Por Verstovsek, Srdan, Mesa, Ruben A., Gotlib, Jason, Levy, Richard S., Gupta, Vikas, DiPersio, John F., Catalano, John V., Deininger, Michael, Miller, Carole, Silver, Richard T., Talpaz, Moshe, Winton, Elliott F., Harvey, Jimmie H., Arcasoy, Murat O., Hexner, Elizabeth, Lyons, Roger M., Paquette, Ronald, Raza, Azra, Vaddi, Kris, Erickson-Viitanen, Susan, Koumenis, Iphigenia L., Sun, William, Sandor, Victor, Kantarjian, Hagop M.
Publicado no N Engl J Med (2012)

Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I

Por Verstovsek, Srdan, Mesa, Ruben A., Gotlib, Jason, Levy, Richard S., Gupta, Vikas, DiPersio, John F., Catalano, John V., Deininger, Michael W.N., Miller, Carole B., Silver, Richard T., Talpaz, Moshe, Winton, Elliott F., Harvey, Jimmie H., Arcasoy, Murat O., Hexner, Elizabeth O., Lyons, Roger M., Paquette, Ronald, Raza, Azra, Vaddi, Kris, Erickson-Viitanen, Susan, Sun, William, Sandor, Victor, Kantarjian, Hagop M.
Publicado em 2013

Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies

Por Mesa, Ruben A., Kiladjian, Jean-Jacques, Verstovsek, Srdan, Al-Ali, Haifa Kathrin, Gotlib, Jason, Gisslinger, Heinz, Levy, Richard, Siulnik, Andres, Gupta, Vikas, Khan, Mahmudul, DiPersio, John F., McQuitty, Mari, Catalano, John V., Hunter, Deborah S., Knoops, Laurent, Deininger, Michael, Cervantes, Francisco, Miller, Carole, Vannucchi, Alessandro M., Silver, Richard T., Barbui, Tiziano, Talpaz, Moshe, Barosi, Giovanni, Winton, Elliott F., Mendeson, Estella, Harvey, Jimmie H., Arcasoy, Murat O., Hexner, Elizabeth, Lyons, Roger M., Paquette, Ronald, Raza, Azra, Sun, William, Sandor, Victor, Kantarjian, Hagop M., Harrison, Claire
Publicado em 2014