Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

Here we demonstrate that protein-coding RNA transcripts can crosstalk by competing for common microRNAs, with microRNA response elements as the foundation of this interaction. We have termed such RNA transcripts as competing endogenous RNAs (ceRNAs). We tested this hypothesis in the context of PTEN,...

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Detaylı Bibliyografya
Asıl Yazarlar: Tay, Yvonne, Kats, Lev, Salmena, Leonardo, Weiss, Dror, Tan, Shen Mynn, Ala, Ugo, Karreth, Florian, Poliseno, Laura, Provero, Paolo, Di Cunto, Ferdinando, Lieberman, Judy, Rigoutsos, Isidore, Pandolfi, Pier Paolo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235920/
https://ncbi.nlm.nih.gov/pubmed/22000013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.09.029
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