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A ceRNA hypothesis: the Rosetta stone of a hidden RNA language?

Here we present a unifying hypothesis about how messenger RNAs, transcribed pseudogenes, and long non-coding RNAs “talk” to each other using microRNA response elements (MREs) as letters of a new language. We propose that this “competing endogenous RNA” (ceRNA) activity forms a large-scale regulatory...

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Détails bibliographiques
Auteurs principaux: Salmena, Leonardo, Poliseno, Laura, Tay, Yvonne, Kats, Lev, Pandolfi, Pier Paolo
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235919/
https://ncbi.nlm.nih.gov/pubmed/21802130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.014
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