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Characterization of dual PTEN and p53-targeting microRNAs identifies microRNA-638/Dnm2 as a two-hit oncogenic locus
Tumor suppressor genes (TSGs) are often concomitantly lost or mutated in human cancers and have been shown to act synergistically to promote tumorigenesis. In addition to genomic alterations, post-transcriptional regulation by microRNAs (miRNAs) represents another mechanism by which TSG expression i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4128194/ https://ncbi.nlm.nih.gov/pubmed/25088422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.064 |
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