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Adenosine A2a receptor antagonists attenuate striatal adaptations following dopamine depletion
The motor symptoms of Parkinson’s disease (PD) are widely thought to arise from an imbalance in the activity of the two major striatal efferent pathways following the loss of dopamine (DA) signaling. In striatopallidal, indirect pathway spiny projection neurons (iSPNs), intrinsic excitability rises...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235740/ https://ncbi.nlm.nih.gov/pubmed/21964253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.08.030 |
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