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Adenosine A2a receptor antagonists attenuate striatal adaptations following dopamine depletion

The motor symptoms of Parkinson’s disease (PD) are widely thought to arise from an imbalance in the activity of the two major striatal efferent pathways following the loss of dopamine (DA) signaling. In striatopallidal, indirect pathway spiny projection neurons (iSPNs), intrinsic excitability rises...

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Bibliografische gegevens
Hoofdauteurs: Peterson, Jayms D., Goldberg, Joshua A., Surmeier, D. James
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235740/
https://ncbi.nlm.nih.gov/pubmed/21964253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.08.030
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