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The cardiovascular biology of microsomal prostaglandin E synthase-1
Both traditional and purpose designed nonsteroidal anti-inflammatory drugs (NSAIDs), selective for inhibition of cyclooxygenase (COX) -2 alleviate pain and inflammation but confer a cardiovascular hazard, attributable to inhibition of COX-2 derived prostacyclin (PGI(2)). Deletion of microsomal PGE s...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235702/ https://ncbi.nlm.nih.gov/pubmed/22137640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2011.04.002 |
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