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RAM/Fam103a1 Is Required for mRNA Cap Methylation
The 7-methylguanosine cap added to the 5′ end of mRNA is required for efficient gene expression in eukaryotes. In mammals, methylation of the guanosine cap is catalyzed by RNMT (RNA guanine-7 methyltransferase), an enzyme previously thought to function as a monomer. We have identified an obligate co...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235549/ https://ncbi.nlm.nih.gov/pubmed/22099306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.08.041 |
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