mRNA Cap Methylation in Pluripotency and Differentiation

The mRNA cap recruits factors essential for transcript processing and translation initiation. We report that regulated mRNA cap methylation is a feature of embryonic stem cell (ESC) differentiation. Expression of the mRNA cap methyltransferase activating subunit RAM is elevated in ESCs, resulting in...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Grasso, Laura, Suska, Olga, Davidson, Lindsay, Gonatopoulos-Pournatzis, Thomas, Williamson, Ritchie, Wasmus, Lize, Wiedlich, Simone, Peggie, Mark, Stavridis, Marios P., Cowling, Victoria H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977272/
https://ncbi.nlm.nih.gov/pubmed/27452456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.089
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