Vangl2 promotes Wnt/Planar Cell Polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance

Although growing body of evidence supports that Wnt-Frizzled signaling controls axon guidance from vertebrates to worms, whether and how this is mediated by planar cell polarity (PCP) signaling remains elusive. We show here that the core PCP components are required for Wnt5a-stimulated outgrowth and...

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Bibliografiske detaljer
Main Authors: Shafer, Beth, Onishi, Keisuke, Lo, Charles, Colakoglu, Gulsen, Zou, Yimin
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235522/
https://ncbi.nlm.nih.gov/pubmed/21316586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.01.002
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