Deletion of Densin-180 Results in Abnormal Behaviors Associated with Mental Illness and Reduces mGluR5 and DISC1 in the Postsynaptic Density Fraction

Densin is an abundant scaffold protein in the postsynaptic density (PSD) that forms a high-affinity complex with αCaMKII and α-actinin. To assess the function of densin, we created a mouse line with a null mutation in the gene encoding it (LRRC7). Homozygous knock-out mice display a wide variety of...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Carlisle, Holly J., Luong, Tinh N., Medina-Marino, Andrew, Schenker, Leslie, Khorosheva, Eugenia, Indersmitten, Tim, Gunapala, Keith M., Steele, Andrew D., O'Dell, Thomas J., Patterson, Paul H., Kennedy, Mary B.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2011
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235477/
https://ncbi.nlm.nih.gov/pubmed/22072671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5877-10.2011
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires