Antitumor Activity of Sorafenib in Human Cancer Cell Lines with Acquired Resistance to EGFR and VEGFR Tyrosine Kinase Inhibitors

Treatment of non small cell lung cancer (NSCLC) and colorectal cancer (CRC) have substantially changed in the last years with the introduction of epidermal growth factor receptor (EGFR) inhibitors in the clinical practice. The understanding of mechanisms which regulate cells sensitivity to these dru...

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Bibliographic Details
Main Authors: Morgillo, Floriana, Martinelli, Erika, Troiani, Teresa, Orditura, Michele, De Vita, Ferdinando, Ciardiello, Fortunato
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235154/
https://ncbi.nlm.nih.gov/pubmed/22174910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028841
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