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Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility

Long interspersed element-1 (LINE-1 or L1) retrotransposons account for nearly 17% of human genomic DNA and represent a major evolutionary force that has reshaped the structure and function of the human genome. However, questions remain concerning both the frequency and the developmental timing of L...

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Autors principals: Wissing, Silke, Muñoz-Lopez, Martin, Macia, Angela, Yang, Zhiyuan, Montano, Mauricio, Collins, William, Garcia-Perez, Jose Luis, Moran, John V., Greene, Warner C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235014/
https://ncbi.nlm.nih.gov/pubmed/21989055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr455
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