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Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility
Long interspersed element-1 (LINE-1 or L1) retrotransposons account for nearly 17% of human genomic DNA and represent a major evolutionary force that has reshaped the structure and function of the human genome. However, questions remain concerning both the frequency and the developmental timing of L...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235014/ https://ncbi.nlm.nih.gov/pubmed/21989055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr455 |
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