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The C-Terminal αI Domain Linker as a Critical Structural Element in the Conformational Activation of αI Integrins
The activation of α/β heterodimeric integrins is the result of highly coordinated rearrangements within both subunits. The molecular interactions between the two subunits, however, remain to be characterized. In this study, we use the integrin α(L)β(2) to investigate the functional role of the C-lin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3234956/ https://ncbi.nlm.nih.gov/pubmed/21965670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.282830 |
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