A Distinct Mechanism for Coactivator versus Corepressor Function by Histone Methyltransferase G9a in Transcriptional Regulation

Histone methyltransferase G9a has been understood primarily as a corepressor of gene expression, but we showed previously that G9a positively regulates nuclear receptor-mediated transcription in reporter gene assays. Here, we show that endogenous G9a contributes to the estradiol (E(2))-dependent ind...

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Main Authors: Purcell, Daniel J., Jeong, Kwang Won, Bittencourt, Danielle, Gerke, Daniel S., Stallcup, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Gene Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234941/
https://ncbi.nlm.nih.gov/pubmed/21984853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.298463
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