Corepressor/coactivator paradox: potential constitutive coactivation by corepressor splice variants

The functional consequences of the interaction of transcriptional coregulators with the human thyroid hormone receptor (TR) in mammalian cells are complex. We have used the yeast, Saccharomyces cerevisiae, which lack endogenous nuclear receptors (NRs) and NR coregulators, as a model to decipher mech...

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Bibliographische Detailangaben
Hauptverfasser: Meng, Xianwang, Arulsundaram, Vishnuka D., Yousef, Ahmed F., Webb, Paul, Baxter, John D., Mymryk, Joe S., Walfish, Paul G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Nuclear Receptor Signaling Atlas 2006
Schlagworte:
Perspective
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630687/
https://ncbi.nlm.nih.gov/pubmed/17088938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1621/nrs.04022
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