Corepressor/coactivator paradox: potential constitutive coactivation by corepressor splice variants

The functional consequences of the interaction of transcriptional coregulators with the human thyroid hormone receptor (TR) in mammalian cells are complex. We have used the yeast, Saccharomyces cerevisiae, which lack endogenous nuclear receptors (NRs) and NR coregulators, as a model to decipher mech...

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Autores principales: Meng, Xianwang, Arulsundaram, Vishnuka D., Yousef, Ahmed F., Webb, Paul, Baxter, John D., Mymryk, Joe S., Walfish, Paul G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Nuclear Receptor Signaling Atlas 2006
Materias:
Perspective
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630687/
https://ncbi.nlm.nih.gov/pubmed/17088938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1621/nrs.04022
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